An Integrated Hierarchical Bayesian Model for Multivariate eQTL Mapping
نویسندگان
چکیده
منابع مشابه
An integrated hierarchical Bayesian model for multivariate eQTL mapping.
Recently, expression quantitative loci (eQTL) mapping studies, where expression levels of thousands of genes are viewed as quantitative traits, have been used to provide greater insight into the biology of gene regulation. Originally, eQTLs were detected by applying standard QTL detection tools (using a "one gene at-a-time" approach), but this method ignores many possible interactions between g...
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Identifying the genetic basis of complex traits remains an important and challenging problem with the potential to impact a broad range of biological endeavors. A number of statistical methods are available for mapping quantitative trait loci (QTL), but their application to high throughput phenotypes has been limited as most require user input and interaction. Recently, methods have been develo...
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ژورنال
عنوان ژورنال: Statistical Applications in Genetics and Molecular Biology
سال: 2012
ISSN: 1544-6115
DOI: 10.1515/1544-6115.1760